Molecular evidence of mixed P. vivax and P. falciparum infections in northern Islamic Republic of Iran
- 13 May 2004
- journal article
- research article
- Published by World Health Organization Regional Office for the Eastern Mediterranean (WHO/EMRO) in Eastern Mediterranean Health Journal
- Vol. 10 (3) , 336-342
- https://doi.org/10.26719/2004.10.3.336
Abstract
This study compared basic microscopy with molecular detection of Plasmodium species. According to thick-film microscopy, 100% of 142 malaria cases in Pars-Abad, Ardebil province, were infected with a single species, P vivax. However, nested polymerase chain reaction (PCR) detected mixed species infections of both P. vivax and P. falciparum in 7.0%. In Mazanderan province, 2/20 blood films were diagnosed with only P. falciparum and 18/20 with only P. vivax. However, nested PCR detected 17/20, 2/20 and 1/20 with P. vivax only, P. falciparum only and mixed species respectively. The unexpected presence of P. falciparum urges prompt investigation and immediate treatment of malaria cases in this region.Keywords
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