Synthesis and Biological Evaluation of Dideoxunucleosides Containing A Difluoromethylene Unit
- 1 January 1989
- journal article
- abstracts
- Published by Taylor & Francis in Nucleosides, Nucleotides and Nucleic Acids
- Vol. 8 (5) , 1111-1114
- https://doi.org/10.1080/07328318908054301
Abstract
2′-difluoro and 3′-difluoro dideoxynucleosides containing thymine and cytosine as the base were synthesized. These compounds inhibited HeLa cell growth and Moloney leukemia virus to a modest degree.Keywords
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