Backward Spreading of Memory-Retrieval Signal in the Primate Temporal Cortex
Top Cited Papers
- 26 January 2001
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 291 (5504) , 661-664
- https://doi.org/10.1126/science.291.5504.661
Abstract
Bidirectional signaling between neocortex and limbic cortex has been hypothesized to contribute to the retrieval of long-term memory. We tested this hypothesis by comparing the time courses of perceptual and memory-retrieval signals in two neighboring areas in temporal cortex, area TE (TE) and perirhinal cortex (PRh), while monkeys were performing a visual pair-association task. Perceptual signal reached TE before PRh, confirming its forward propagation. In contrast, memory-retrieval signal appeared earlier in PRh, and TE neurons were then gradually recruited to represent the sought target. A reasonable interpretation of this finding is that the rich backward fiber projections from PRh to TE may underlie the activation of TE neurons that represent a visual object retrieved from long-term memory.Keywords
This publication has 30 references indexed in Scilit:
- Top-down signal from prefrontal cortex in executive control of memory retrievalNature, 1999
- On the Relations among Priming, Conscious Recollection, and Intentional Retrieval: Evidence from Neuroimaging ResearchNeurobiology of Learning and Memory, 1998
- Images of Medial Temporal Lobe Functions in Human Learning and MemoryNeurobiology of Learning and Memory, 1998
- Hierarchical organization of cognitive memoryPhilosophical Transactions Of The Royal Society B-Biological Sciences, 1997
- Visual Object RecognitionAnnual Review of Neuroscience, 1996
- Inferotemporal Cortex and Object VisionAnnual Review of Neuroscience, 1996
- Perirhinal and parahippocampal cortices of the macaque monkey: Cortical afferentsJournal of Comparative Neurology, 1994
- Interhemispheric sharing of visual memory in macaquesBehavioural Brain Research, 1994
- Inferior Temporal Cortex: Where Visual Perception Meets MemoryAnnual Review of Neuroscience, 1993
- Neural organization for the long-term memory of paired associatesNature, 1991