Improved Survival of Iron-Deficient Patients with Sickle Erythrocytes

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Abstract
To the Editor: Recently we described the clinical and hematologic features of sickle-cell disease in adult patients who also had iron-deficiency anemia due to blood loss.1 We now report the results of red-cell-survival studies that were carried out in one of these patients during the period of iron deficiency and after its correction.A 45-year-old woman with sickle-cell anemia and uterine bleeding from endomctrial hyperplasia (Case 4 in reference 1) was injected with autologous 51Cr-labeled2 red cells while she was still iron-deficient, and red-cell survival was measured for the next three weeks. During this period the hemoglobin level remained . . .

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