Differences in the Effect of Actinomycin D on Estrogen-Stimulated Mouse Uterine Weight and on the Activity of Some Uterine Enzymes
- 1 February 1966
- journal article
- research article
- Published by The Endocrine Society in Endocrinology
- Vol. 78 (2) , 286-290
- https://doi.org/10.1210/endo-78-2-286
Abstract
Intraperitoneal administration of actinomycin D resulted in inhibition of estrogen-stimulated uterine weight in immature mice. Estrogen-stimulated uterine carbonic anhydrase activity was inhibited to a much lesser degree than uterine weight. Alkaline phosphatase activity appears to be even more stable. In experiments of 48-hr. duration, actinomycin had to be injected 4 hr. before estradiol in order to achieve inhibition of carbonic anhydrase activity. Inanition can play an important role in the interpretation of these experiments.This publication has 4 references indexed in Scilit:
- HORMONE ANTAGONISTS - INHIBITORS OF SPECIFIC ACTIVITIES OF ESTROGEN AND ANDROGEN1964
- TESTICULAR HORMONES AND THE SYNTHESIS OF RIBONUCLEIC ACIDS AND PROTEINS IN THE PROSTATE GLAND1964
- CARBONIC ANHYDRASE IN STEROID-RESPONSIVE TISSUES1963
- MICRO-DETERMINATION OF CARBONIC ANHYDRASE ACTIVITY IN ANIMAL TISSUE1Endocrinology, 1960