THE EFFECT OF N-ACETYLNEURAMINIC ACID ON THE MUCOCILIARY TRANSPORT IMPAIRED BY CIGARETTE-SMOKE
- 1 November 1988
- journal article
- research article
- Vol. 296, 202-209
Abstract
Cigarette smoke exposure imapired the mucociliary transport on the tracheal mucosa of pigeons. N-acetylneuraminic acid (NANA), but not lactose, dose-dependently protected against the impairment of the mucociliary transport. The results suggest the NANA, a representative sialic acid existing on the airway epithelium, may participate in the defence mechanism in the respiratory tract against irritant gases.This publication has 8 references indexed in Scilit:
- SECRETOMOTOR AND MUCOLYTIC EFFECTS OF MABUTEROL, A NOVEL BRONCHODILATOR1987
- Evidence for mucins and sialic acid as receptors for Pseudomonas aeruginosa in the lower respiratory tractInfection and Immunity, 1983
- Cigarette smoke inhibition of ion transport in canine tracheal epithelium.Journal of Clinical Investigation, 1983
- Mucociliary Clearance in Patients with Chronic Bronchitis and Bronchial CarcinomaRespiration, 1983
- CIGARETTE-SMOKING AND LUNG DESTRUCTION - ACCUMULATION OF NEUTROPHILS IN THE LUNGS OF CIGARETTE SMOKERSPublished by Elsevier ,1983
- ABNORMAL MUCOCILIARY TRANSPORT IN ALLERGIC PATIENTS WITH ANTIGEN-INDUCED BRONCHOSPASM - ROLE OF SLOW REACTING SUBSTANCE OF ANAPHYLAXISPublished by Elsevier ,1981
- RELATIONSHIP OF SMOKING HISTORY AND PULMONARY-FUNCTION TESTS TO TRACHEAL MUCOUS VELOCITY IN NON-SMOKERS, YOUNG SMOKERS, EX-SMOKERS, AND PATIENTS WITH CHRONIC-BRONCHITISPublished by Elsevier ,1978
- Components of Cigarette Smoke with Ciliary-Depressant ActivityNew England Journal of Medicine, 1963