Synthesis and Binding Properties of Ethylbipyridinio-Modified β-Cyclodextrin

Abstract
Mono-6-deoxy-6-[4-(1-ethyl-4-pyridinio)-1-pyridinio]-β-cyclodextrin (3) was synthesized. The conformation and the binding properties of 3 with benzene derivatives were examined by induced circular dichroism (ICD) in aqueous solution. The conformation of 3 was confirmed to such equatorial inclusion as β-CDx capped by ethylviologen (C2V2+) group. Further, compound 3 showed stronger binding ability with these guests (1:1 complexes) compared with β-cyclodextrin (β-CDx).

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