Effect of Dietary Lysine Level on Certain Blood Patterns in Growing Swine

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Abstract
Two trials were conducted with growing swine. The first trial was to determine the effect of lysine level on blood cell count, hematocrit and hemoglobin values, sedimentation rate and serum proteins. The second was to study further the effect lysine level had on these blood patterns and to determine whether antibiotic or sex alter these patterns at two lysine levels. Pigs in the first trial received a 16% protein corn-peanut oil meal ration supplemented with 0.0, 0.3, 0.6, 0.9, and 1.2% L-lysine HC1. A sixth lot received a corn-soybean oil meal ration. In the second trial lot 1 received the corn-peanut oil meal basal, while lot 2 received this plus 10 mg. antibiotic per pound of feed. Lot 3 received the basal plus 0.6% L-lysine HC1, and lot 4 received the antibiotic and lysine. Protein levels were reduced to 14 and 12% at 75 and 125 lb., respectively. Lysine supplementation was decreased at a proportional rate. Data are presented which indicate that lysine supplementation resulted in decreased white cell count, gamma globulin level, and sedimentation rate, and increases in hematocrit value, red cell count, hemoglobin level, total serum protein level and serum albumin level. Figures showing the blood protein fractions indicate that serum albumin patterns might become useful as a measure of protein adequacy. Data of trial 2 confirm much of that from trial 1, but show that antibiotic increased sedimentation rate. Significant interaction between the effect of lysine and antibiotic were shown in sedimentation rate and hematocrit value.