Revised enzyme synthesis rate expression in cybernetic models of bacterial growth
- 1 January 1988
- journal article
- research article
- Published by Wiley in Biotechnology & Bioengineering
- Vol. 31 (1) , 41-43
- https://doi.org/10.1002/bit.260310107
Abstract
A revised enzyme synthesis rate expression for cybernetic models of bacterial growth is presented. The rate expression, which is comprised of inducible and constitutive contributions, provides for a basal enzyme level that is necessary to predict certain types of commonly observed continuous culture transients. The response of a continuous culture to a step change in feed stream composition is simulated using both the old and new formulations, and the ramifications for the “matching-law” formulation are discussed.Keywords
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