Reply to Penack et al. and Wu

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Abstract
Sir—In their letter, Penack et al. [1] question the reliability of the association between false-positive galactomannan (GM) antigenemia results obtained with use of the Platelia Aspergillus ELISA (Bio-Rad) and piperacillin-tazobactam treatment. To date, outbreaks of false-positive results during surveillance of GM antigenemia have been reported by 3 European centers caring for patients with hematological abnormalities (2 centers in France [2, 3] and 1 in Italy [3]). In France, moreover, several other centers experienced the same phenomenon starting in May 2003 and alerted the Agence Française de Sécurité Sanitaire des Produits de Santé, which is the French health products safety agency.