Early alveolar clearance in rabbits intermittently exposed to sulfuric acid mist

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Abstract
During the course of 1‐h/d, 5‐dlwk exposure to submicrometer sulfuric acid mist at 250 μg/m3, rabbits were exposed to a radioactively tagged polystyrene latex tracer aerosol to assess clearance from the alveolar region during the period 2–14 d after tracer exposure. The latex was administered on d 1, 57, and 240 following the start of the H2SO4 exposures. Early alveolar clearance was found to be accelerated during the first test, and this acceleration was maintained throughout the 8‐mo monitoring period.