Cell Aggregation: Role of Acid Mucopolysaccharides
- 25 February 1972
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 175 (4024) , 898-900
- https://doi.org/10.1126/science.175.4024.898
Abstract
Factors that induce cell aggregation are released by several types of chick embryo and mammalian cell cultures. These aggregation factors are also present in some serums. The factors in each of the preparations tested were inactivated by treatment with bovine testicular hyaluronidase. Conversely, hyaluronic acid promoted aggregation of only those cells that were aggregated by media containing the factors. These factors appear to be acid mucopolysaccharides, with hyaluronic acid being a major component.Keywords
This publication has 22 references indexed in Scilit:
- Production and secretion of chondroitin sulfates and dermatan sulfate by established mammalian cell linesBiochemical and Biophysical Research Communications, 1971
- Aggregation of mouse malignant tissue culture cells at +6 °CExperimental Cell Research, 1970
- Cell aggregation: Properties of specific cell-ligands and their role in the formation of multicellular systemsDevelopmental Biology, 1968
- Cell surface components participating in aggregation: Evidence for a new cell particulateExperimental Cell Research, 1965
- The production of hyaluronate by spontaneously established cell lines and viral transformed lines of fibroblastic originBiochimica et Biophysica Acta (BBA) - Mucoproteins and Mucopolysaccharides, 1965
- Characterization of specific cell aggregating materials from sponge cellsBiochemical and Biophysical Research Communications, 1965
- Aggregation of Cultured Mammalian CellsNature, 1963
- Chemical dissolution and in vitro reconstruction of sponge cell adhesionsDevelopmental Biology, 1963
- Characterization of resistance to amethopterin, 8‐azaguanine and several fluorinated pyrimidines in the murine lymphocytic neoplasm, P388Journal of Cellular and Comparative Physiology, 1962
- COMPARATIVE STUDIES IN ROUS SARCOMA WITH VIRUS, TUMOR CELLS, AND CHICK EMBRYO CELLS TRANSFORMED IN VITRO BY VIRUSThe Journal of Experimental Medicine, 1961