Abstract
Transcutaneous electrical nerve stimulation (TENS) at high frequency and high intensity caused human pain threshold elevation for thermal stimuli only when thermal stimuli were applied at a site distal to the TENS electrodes. High-frequency TENS applied over the belly of m. biceps brachii did not cause a marked misestimation of elbow angle at any of the TENS intensities used. It is concluded that pain threshold elevation during high-frequency TENS is due to peripheral electrogenic blockade or fatigue of pain-mediating fibers. A minor effect of TENS on kinesthesia suggests a minor role of muscle afferents in mediating the effects of high-frequency TENS.

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