MICROINVASIVE SQUAMOUS CARCINOMA OF CERVIX - DEFINITION, HISTOLOGIC ANALYSIS, LATE RESULTS OF TREATMENT

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  • 1 January 1977
    • journal article
    • research article
    • Vol. 50  (4) , 410-414
Abstract
The surgical tissues and clinical records of 54 surgically treated patients with microinvasive carcinoma of the cervix were retrospectivley analyzed. Utilizing a definition that limited microinvasion to a depth of 3 mm, and excluded lymphatic and blood vascular involvement, the incidence of regional metastases in 37 patients for whom lymph nodes were available for study was 0%. Confluence of microinvasion did not imply a greater potential for metastatic spread or a worse prognosis. Lymphatic and blood vascular permeations were associated with nodal metastases in 1 of 4 lesions which otherwise were microinvasive. Random cervical biopsy alone was inadequate for the diagnosis of microinvasion. Cone biopsy demonstrated an accuracy of 83% in diagnoses, but failed to eliminate intraepithelial or microinvasive carcinoma in 78% of the hysterectomy specimens. Microinvasive carcinoma, as defined in this study, can be effectively treated by conservative rather than radical means.