Mutant Products of the NF2 Tumor Suppressor Gene Are Degraded by the Ubiquitin-Proteasome Pathway
Open Access
- 1 August 2002
- journal article
- Published by Elsevier
- Vol. 277 (35) , 31279-31282
- https://doi.org/10.1074/jbc.c200125200
Abstract
No abstract availableKeywords
This publication has 22 references indexed in Scilit:
- The NF2 tumor suppressor gene product, merlin, mediates contact inhibition of growth through interactions with CD44Genes & Development, 2001
- Hierarchy of Merlin and Ezrin N- and C-terminal Domain Interactions in Homo- and Heterotypic Associations and Their Relationship to Binding of Scaffolding Proteins EBP50 and E3KARPJournal of Biological Chemistry, 2001
- Detection of novelNF2 mutations by an RNA mismatch cleavage methodHuman Mutation, 2000
- Ruffling membrane, stress fiber, cell spreading and proliferation abnormalities in human Schwannoma cellsOncogene, 1998
- Impairment of cell adhesion by expression of the mutant neurofibromatosis type 2 (NF2) genes which lack exons in the ERM-homology domainOncogene, 1998
- THE UBIQUITIN SYSTEMAnnual Review of Biochemistry, 1998
- Interdomain binding mediates tumor growth suppression by the NF2 gene productOncogene, 1997
- The Nf2 tumor suppressor gene product is essential for extraembryonic development immediately prior to gastrulation.Genes & Development, 1997
- Alteration in a new gene encoding a putative membrane-organizing protein causes neuro-fibromatosis type 2Nature, 1993
- A novel moesin-, ezrin-, radixin-like gene is a candidate for the neurofibromatosis 2 tumor suppressorCell, 1993