A Randomized Controlled Clinical Trial of the Serotonin Type 3 Receptor Antagonist Alosetron in Women With Diarrhea-Predominant Irritable Bowel Syndrome
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Open Access
- 23 July 2001
- journal article
- clinical trial
- Published by American Medical Association (AMA) in Archives of internal medicine (1960)
- Vol. 161 (14) , 1733-1740
- https://doi.org/10.1001/archinte.161.14.1733
Abstract
IRRITABLE BOWEL syndrome (IBS) is one of the most common functional gastrointestinal disorders seen in primary care and gastroenterology practices.1,2 Irritable bowel syndrome primarily affects women,3 with prevalence estimates of 14% to 24% of women in the United States and Great Britain.4 It negatively affects patients' daily activities and quality of life5-7 and contributes to significant increases in health care resource utilization.5,8Keywords
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