Abstract
An introduction of a symposium on cardiovascular regulation. The concept of regulation is defined as a framework for the succeeding papers. For regulation of a function to occur the system must possess a receptor sensitive to the function, feedback information regarding the real magnitude of the function, an integrating mechanism which compares the real magnitude with a "set" magnitude and which generates an "error" signal proportional to the difference and that the mechanisms which determine the real magnitude of the function are controlled by the error signal and finally that these aspects of a regulation system comprise a closed loop. Various functions (e.g., blood pressure, blood volume, water and electrolyte, blood flow, etc.) are said to be regulated. The purpose of the symposium is to consider whether or not these functions are regulated.

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