Studies on the Components of Ophiopogon tuber (China). II

Abstract
From Ophiopogon tuber (China), a new borneol derivative (III) and a new steroidal sapogenin named ophiogenin (IV) were isolated in addition to glycerol (I) and .alpha.-humulene (II). The structures of III and IV were established as calcium bornyl sulfate and 25R-spirost-5-en-3.beta.,14.alpha.,17.alpha.-triol on the basis of several spectral data. The antimicrobial activities for the isolated constituents from Ophiopogon tuber were examined. As a result, 25S-ruscogenin and a mixture of ruscogenin and 25S-ruscogenin showed antimicrobial activities of Gram-positive bacteria.

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