Comparison of efficacy of thrombolysin, streptokinase, and urokinase in a femoral vein clot model in rats

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Abstract
A venous clot model in rats was used to compare the ability of locally infused thrombolytic agents to lyse clots. Urokinase and a combination of streptokinase and human plasminogen (Thrombolysin) proved to be equally effective in lysing clots. In comparison, streptokinase alone was not as effective a thrombolytic agent in this model.