Propoxyphene (Darvon) Poisoning

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Abstract
Propoxyphene (Darvon) has been widely used since its introduction in 1957. That propoxyphene can cause severe and potentially fatal respiratory depression in humans is not well known. This case is reported to acquaint the reader with the depressing action of propoxyphene and also the role of nalorphine (or levallorphan) as an antidotal antagonist for propoxyphene-induced respiratory depression. Report of a Case A four-year-old male was supposedly playing quietly with his younger sister while his mother took a Sunday morning nap. His mother awoke and thought her son did not look well. She left the living room to dress. When she returned five minutes later the boy was lying on his back on the sofa having a generalized convulsion. His breathing was noisy and gasping, and his lips were blue. A frantic phone call brought me to the apartment as soon as possible. The mother gave no information about recent exposure

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