Bryophyte Constituents; 7: New Synthesis of (+)-Rosmarinic Acid and Related Compounds

Abstract
Efficient and expeditious syntheses are described for rosmarinic acid (1) and its derivatives 2-4, making extensive use of allyl protective groups for both carboxylic acids and phenolic building blocks. (+)-(R)-Rosmarinic acid was obtained by a chemoenzymatic resolution of its phenyl lactic acid precursors.

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