Conversion of psoralen DNA monoadducts in E. coli to interstrand DNA cross links by near UV light (320–360 nm): Inability of angelicin to form cross links, in vivo
- 1 March 1977
- journal article
- Published by Springer Nature in Cellular and Molecular Life Sciences
- Vol. 33 (3) , 384-386
- https://doi.org/10.1007/bf02002841
Abstract
Both angelicin and psoralen monoadducts formed in vivo in E. coli by near UV light produce lethal and mutagenic effects. However psoralen monoadducts are converted to cross links by higher doses of UV; angelicin monoadducts are not. The relevance of these results to psoralen photosensitization is discussed.Keywords
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