Antiparasitic agents. 3. Synthesis and anthelmintic activities of novel 2-pyridinyl-5-isothiocyanatobenzimidazoles
- 1 September 1979
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Medicinal Chemistry
- Vol. 22 (9) , 1113-1118
- https://doi.org/10.1021/jm00195a021
Abstract
The preparation and anthelmintic activities of a series of 2-pyridinyl-5-isothiocyanatobenzimidazoles are described. In the primary oral mouse screen, 6 derivatives showed 100% taeniacidal activity at 0.2% in diet. The most active member in this series is potentially an effective gastrointestinal nematocide in sheep at 50 mg/kg per os.This publication has 1 reference indexed in Scilit:
- Advances in the Coordination Chemistry of AzolesRussian Chemical Reviews, 1973