Coexistence of renin and cathepsin B in epithelioid cell secretory granules
- 1 January 1985
- journal article
- research article
- Published by Springer Nature in Histochemistry and Cell Biology
- Vol. 83 (2) , 103-108
- https://doi.org/10.1007/bf00495138
Abstract
Mature juxtaglomerular epithelioid cell secretory granules of the rat exhibit both renin- and cathepsin B-like immunoreactivity. On the basis of the coexistence with renin at a pH which, according to previous experiments, is probably in the range of that in lysosomes, cathepsin B is suggested to be involved in the activation of renin prior to secretion.Keywords
This publication has 36 references indexed in Scilit:
- Identification of plasma inactive renin as prorenin with a site-directed antibodyBiochemical and Biophysical Research Communications, 1985
- Effects of sodium depletion on inactive and active renin from dog kidney and plasma.Hypertension, 1984
- Characterization of inactive renin ("prorenin") from renin-secreting tumors of nonrenal origin. Similarity to inactive renin from kidney and normal plasma.Journal of Clinical Investigation, 1984
- Changes in Salt Intake Alter the Release of Multiple Renin Species in a Nonuniform MannerKidney and Blood Pressure Research, 1984
- Lysosomes revisitedEuropean Journal of Biochemistry, 1983
- A simple post-embedding system for the rapid demonstration of tissue antigens under the electron microscopeJournal of Molecular Histology, 1983
- Lysosomal Cysteine ProteinasesPublished by Wiley ,1980
- Immunocytochemical localization of renin in the submandibular gland of the mouse.Journal of Histochemistry & Cytochemistry, 1978
- Cathepsin LEuropean Journal of Biochemistry, 1977
- On the substrate specificity of cathepsins B1 and B2 including a new fluorogenic substrate for cathepsin B1Life Sciences, 1975