Mortality Differences Between Men and Women Following First Myocardial Infarction

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Abstract
DIFFERENCES in early mortality between men and women who experience acute myocardial infarction (AMI) are related to comorbidity and demographic (ie, age) dissimilarities.1,2 The issue of sex differential in mortality after AMI has been addressed in the context of clinical trials and other investigations that sometimes were not aimed specifically at answering the question of whether some relevant differences remain after controlling for confounding factors, and some authors have reported significant increases even after adjustment for some or all of these factors.3-8 A wide heterogeneity in methods, inclusion criteria, and adjustment procedures as well as exclusion of subgroups of patients from analyses precludes straightforward comparison of results among studies.2

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