The Nature of DNA Synthesized in Nuclei from Mouse L1210 Cells
- 1 May 1977
- journal article
- research article
- Published by Wiley in European Journal of Biochemistry
- Vol. 75 (2) , 347-355
- https://doi.org/10.1111/j.1432-1033.1977.tb11535.x
Abstract
A DNA synthesizing system in vitro from mouse L1210 cell nuclei is described. A high proportion of the DNA synthesized by the L1210 cell nuclei in vitro appeared to be covalently linked complementary DNA. DNA synthesis by L1210 nuclei was not inhibited by the antileukemia compound 4''-(9-acridinylamino)-methansulfon-m-anisidine, although this drug binds to isolated DNA and is active against L1210 leukemia.This publication has 29 references indexed in Scilit:
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