Increased Dental Caries Activity in the Syrian Hamster Following Desalivation.

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Abstract
Parotid, submaxillary and major sublingual glands were removed from 7 hamsters (3 cT c?1, 4 9 9). Desalivation resulted in a sharp reduction in body wt. which, subsequently, remained below that of control groups. The exptl. group and a control group (4 d* d1, 5 9 9) were maintained on a caries producing diet for approx. 75 days. A supplementary control group (8 d1 c?, 9 9 9) consumed the diet for approx. 100 days. Dental caries activity following operation was increased in both 9 and c? animals. The difference was statistically significant in the case of the former but not the latter. It is probable that a comparable response does occur in c? d" but requires a larger number of animals for unequivocal demonstration. Caries response following desalivation was similar to that reported previously for humans.

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