The Histological Effects of Composite Resin Materials on the Pulps of Monkey Teeth

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Abstract
Pulpal response of 3 bis glycol methacrylate composite resins, Smile, Simulate and Experimental Composite #2 were tested on primary and permanent monkey teeth using zinc oxide eugenol (ZOE) and silicate as controls. All materials were placed in Class V cavity preparations in Rhesus monkey teeth and evaluated at 3 days and 5 and 8 wk. The materials were randomly placed in anterior and posterior teeth utilizing 75 primary and 75 permanent teeth. Following perfusion the teeth were prepared by routine histological procedures. The 3 day response of the composite resins was moderate, characterized by disruption of the odontoblasts, vacuolization and a mild inflammatory response underlying the cavity. At 5 wk the formation of reparative dentin and a decrease in the inflammatory response was similar for all resins observed. At 8 wk a slight increase in reparative dentin and a continued decrease in inflammation was noted when compared to the 5 wk responses. At all time intervals ZOE produced the least pulpal response while silicate produced the most severe response.

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