1. 1. A surgically treated cystadenoma of the pancreas is reported and a series of twenty-eight cases collected from the medical literature reviewed. 2. 2. Pathologically cystadenoma of the pancreas is a benign, multilocular, cystic, adenomatous neoplasm which most often originates from the tail or body of the pancreas. 3. 3. Clinically this tumor is characterized by slow growth, absence of early symptoms, and later development of a palpable tumor, upper abdominal pain, and weight loss. 4. 4. Pancreatic cystadenomas occur much more frequently in women than in men (ratio 8:1). 5. 5. Six of twenty-eight patients in this series had associated diabetes mellitus. 6. 6. Complete surgical removal of the tumor is the treatment of choice.