Plasma Proteins in Venous and Cord Blood at Delivery Following Uncomplicated and Complicated Pregnancies

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Abstract
Total protein, albumin and 5 globulin fractions were detd. by electrophoresis in the plasma of samples of cord blood and of venous blood from 11 women whose pregnancies were uncomplicated. Similar samples were analyzed from 21 women whose pregnancies were complicated by toxemia of pregnancy and other diseases. In uncomplicated pregnancy total protein values for venous blood were higher than those for cord blood. Greater avg. amts. of albumin and gamma globulin were found in cord blood than in the corresponding venous blood, coincident with lesser amts. of alpha, beta, and phi globulins. In complicated pregnancies the ranges for total plasma protein in venous and cord blood were lower than those for the normal group. Ranges for serum protein (calculated as plasma minus fibrinogen) fractions in cord blood following complicated pregnancies were, in general, higher for albumin and gamma globulin and lower for alpha, beta, and phi globulins than those for venous blood.