Escherichia coli O114:nonmotile as a Pathogen in an Outbreak of Severe Diarrhea Associated with a Day Care Center

Publisher Website
Google Scholar
Abstract
Five infants from a day care center developed severe diarrhea associated with enteropathogenic Escherichia coli O114:nonmotile (EPEC O114:NM) and required hospitalization. Five additional cases of diarrhea associated with EPEC O114:NM subsequently occurred, four in hospital contacts of the patients and one in a household contact. Biochemically, all EPEC O114:NM isolates were sorbitol nonfermenters. All isolates produced low concentrations of cytotoxin with a mean of 101.23 CD50/mg of protein. Cytotoxin was not neutralized with antibody to Shiga-liketoxin I or II. Heat-labile and heat-stable enterotoxins were not present by gene probe analysis. Stool isolates from 9 of 10 hospitalized infants were positive for EPEC adherence factor by colony blot DNA probe analysis. The severity of the disease, sorbitol non fermentation, and presence of enteroadherence are unusual features of this organism.

This publication has 2 references indexed in Scilit: