Tyrosine 50 at the Subunit Interface of Dimeric Human Glutathione Transferase P1-1 Is a Structural Key Residue for Modulating Protein Stability and Catalytic Function
- 1 April 2000
- journal article
- Published by Elsevier in Biochemical and Biophysical Research Communications
- Vol. 271 (1) , 59-63
- https://doi.org/10.1006/bbrc.2000.2579
Abstract
No abstract availableKeywords
This publication has 37 references indexed in Scilit:
- Crystal Structure of a Murine GlutathioneS-Transferase in Complex with a Glutathione Conjugate of 4-Hydroxynon-2-enal in One Subunit and Glutathione in the Other: Evidence of Signaling across the Dimer Interface,Biochemistry, 1999
- Benzoic acid derivatives induce recovery of catalytic activity in the partially inactive Met208Lys mutant of human glutathione transferase A1-1 1 1Edited by A. R. FershtJournal of Molecular Biology, 1999
- Mutations of gly to ala in human glutathione transferase P1-1 affect helix 2 (G-site) and induce positive cooperativity in the binding of glutathione 1 1Edited by R. HuberJournal of Molecular Biology, 1998
- Molecular Phylogeny of Glutathione-S-TransferasesDNA and Cell Biology, 1997
- Structure, Catalytic Mechanism, and Evolution of the Glutathione TransferasesChemical Research in Toxicology, 1997
- Site-directed Mutagenesis of Human Glutathione Transferase P1-1: MUTATION OF Cys-47 INDUCES A POSITIVE COOPERATIVITY IN GLUTATHIONE TRANSFERASE P1-1Published by Elsevier ,1995
- The Glut athione S-Transferase Supergene Family: Regulation of GST and the Contribution of the lsoenzymes to Cancer Chemoprotection and Drug Resistance Part ICritical Reviews in Biochemistry and Molecular Biology, 1995
- Nomenclature for human glutathione transferasesBiochemical Journal, 1992
- Glutathione Transferases—Structure and Catalytic ActivitCritical Reviews in Biochemistry, 1988
- Kinetic independence of the subunits of cytosolic glutathione transferase from the ratBiochemical Journal, 1985