EVALUATION OF A MICRO-VASCULAR PROSTHESIS OF MICROPOROUS POLYTETRAFLUOROETHYLENE IN RATS

  • 1 January 1982
    • journal article
    • research article
    • Vol. 154  (5) , 673-680
Abstract
Polytetrafluoroethylene grafts were used as a microvascular prosthetic material in rats with a patency rate of 75%. Immediate evaluation of the interface by scanning electron microscopy and histologic examination confirm the blood compatibility of the material, i.e., limited platelet and erythrocytic activation or fibrin formation or both. However, a longer evaluation period, as great as 3 mo., fails to demonstrate the development of an endothelial lining which does not cross over the suture lines. Similarly, at this time, the immediate adjacent artery also remains devoid of typical endothelial structure. Endothelial reconstitution, if present, even on normal substructures, apparently remains a delayed process.

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