Abstract
A cooperage is described in which a severe Pb hazard caused 2 cases of Pb poisoning; one patient developed encephalopathy. The syndrome of Pb encephalopathy in adults is reviewed. The difficulties in diagnosis, the possible causes of apparent susceptibility to Pb, the absence of hypertension in this and other cases, and the treatment of encephalopathy are discussed. Some of the essential differences between this form of encephalopathy and that due to tetraethyl lead are outlined.