Oxygen-17 Contrast Agents Fast Imaging Techniques
- 1 September 1988
- journal article
- research article
- Published by Wolters Kluwer Health in Investigative Radiology
- Vol. 23, S240-S242
- https://doi.org/10.1097/00004424-198809001-00050
Abstract
Under physiologic conditions the stable isotope oxygen-17, in the form of O-17 water, lowers the proton T2 of blood, CSF, tissues, and whole organisms. With MRI the resulting changes in intensity can be detected using spin-echo pulse sequences, but much greater sensitivity is achieved in a fraction of the time with a steady-state free precession sequence such as FISP. With this sequence it is possible to detect levels as low as 0.4% Oxygen-17 water in 53 seconds or less.Keywords
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