Amiodarone N-deethylation in human liver microsomes : Involvement of cytochrome P450 3A enzymes (first report)
- 1 January 1993
- journal article
- research article
- Published by Elsevier in Life Sciences
- Vol. 52 (10) , PL91-PL96
- https://doi.org/10.1016/0024-3205(93)90523-6
Abstract
No abstract availableKeywords
This publication has 16 references indexed in Scilit:
- High-performance liquid chromatographic assay for amiodarone N-deethylation in microsomes of rat liverJournal of Chromatography B: Biomedical Sciences and Applications, 1992
- AmiodaroneDrugs, 1992
- The P450 Superfamily: Update on New Sequences, Gene Mapping, and Recommended NomenclatureDNA and Cell Biology, 1991
- Species Differences in Metabolism and Pharmacokinetics: Are We Close to an Understanding?Drug Metabolism Reviews, 1991
- Genotyping of poor metabolisers of debrisoquine by allele-specific PCR amplificationThe Lancet, 1990
- In vitro hepatic, renal, and pulmonary N-dealkylation of amiodaroneBiochemical Pharmacology, 1990
- Basic and Clinical Pharmacology of Amiodarone: Relationship of Antiarrhythmic Effects, Dose and Drug Concentrations to Intracellular Inclusion BodiesThe Journal of Clinical Pharmacology, 1989
- Identification of glucocorticoid-inducible cytochromes P-450 in the intestinal mucosa of rats and man.Journal of Clinical Investigation, 1987
- AmiodaroneNew England Journal of Medicine, 1987
- Inhibition of oxidative drug metabolism in microsomesPharmacology & Therapeutics, 1980