On the incidence of blood group O and Gm(−1) phenotypes in patients with malignant melanoma

31 December 1978

journal article
research article
Published by Springer Nature in Human Genetics

Vol. 49 (1) , 71-81
https://doi.org/10.1007/bf00277688

Abstract

Summary Fifteen polymorphic systems of the blood (ABO, MNSs, Rhesus, P, Kell, Duffy, Kidd, Hp, Gc, Gm, Inv, aP, PGM₁, EsD, and 6-PGD) were examined in 191 unrelated male and female patients suffering from malignant melanoma. These polymorphic systems were compared with the corresponding phenotype and gene frequencies of controls from the same geographical area (Rhineland-Palatinate). The only associations discovered were the ABO and Gm polymorphisms: The incidence of O and Gm(-1) phenotypes in patients is obviously higher than in controls. These observations agree with the findings in other population samples from Germany and Bulgaria.

Keywords

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