Mononuclear Cell Adherence to Cultured Endothelium Is Enhanced by Hypertension and Insulin Resistance in Healthy Nondiabetic Volunteers
- 31 August 1999
- journal article
- other
- Published by Wolters Kluwer Health in Circulation
- Vol. 100 (9) , 940-943
- https://doi.org/10.1161/01.cir.100.9.940
Abstract
Background —This study was initiated to compare the adherence to cultured endothelial cells of mononuclear cells isolated from normotensive and hypertensive individuals. Methods and Results —Mononuclear cell binding to endothelium was greater in patients with hypertension (32±1 versus 25±2; P r =0.42, P r =0.86, P r =0.74, P P Conclusions —These results indicate that both hypertension and insulin resistance lead to changes in mononuclear cells that increase their adherence to cultured endothelial cells.Keywords
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