Effect of Low Temperature and Work on Blood Lactic Acid in Deer Mice

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Abstract
Except occasionally during intense shivering, blood lactic acid of resting deer mice (Peromyscus maniculatus gracilis, Le Conte) remained within normal limits at temps. from 30[degree]C. to -27[degree] C, even though the O2 consumption at the lowest temp. was increased to 7 times that observed at 30[degree] C. Normal lactate values were also found at the point of death in the cold. On the other hand, a pronounced increase in lactate was found in running mice at 30[degree] C. when the O2 consumption had increased only 3-5 times the resting rate. After the same amt. of work, lactate levels were approx. equal at room temp. (22[degree] C.) and in the cold (0[degree]C). The observations suggest differences in the site of energy release during work and cold exposure, and various hypotheses, including the contribution of non-muscular tissue, are discussed.

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