Absence of platelet response after eradication of Helicobacter pylori infection in patients with chronic idiopathic thrombocytopenic purpura
- 20 December 2001
- journal article
- research article
- Published by Wiley in British Journal of Haematology
- Vol. 115 (4) , 1002-1003
- https://doi.org/10.1046/j.1365-2141.2001.03194.x
Abstract
Eradication of Helicobacter pylori infection has been associated with the correction of thrombocytopenia in patients with idiopathic thrombocytopenic purpura (ITP). We have analysed the response to eradication of H. pylori in a series of 56 adult patients with chronic ITP. Forty patients had H. pylori infection (71%) that was eradicated in 23 of 32 evaluable patients (72%). Platelet counts did not significantly vary according to H. pylori treatment outcome. Three of 56 patients (5%) achieved a partial response attributable to H. pylori eradication. Therefore, detection of H. pylori infection should not be routinely included in the initial work‐up of ITP.Keywords
This publication has 3 references indexed in Scilit:
- Helicobacter pylori eradication can induce platelet recovery in idiopathic thrombocytopenic purpuraBlood, 2001
- Regression of autoimmune thrombocytopenia after eradication of Helicobacter pyloriThe Lancet, 1998
- Idiopathic thrombocytopenic purpura: a practice guideline developed by explicit methods for the American Society of Hematology [see comments]Blood, 1996