EFFECT OF 6-HYDROXYDOPAMINE ON TUMOR-GROWTH

  • 1 January 1976
    • journal article
    • research article
    • Vol. 36  (7) , 2382-2384
Abstract
The growth of C-1300 neuroblastoma was markedly slowed in 6-hydroxydopamine-treated mice. The growth of the A-10 breast adenocarcinoma was also significantly retarded in 6-hydroxydopamine-treated mice, but the growth of B-16 melanoma was not affected. In mice axotomized by pretreatment with 6-hydroxydopamine the growth of C-1300 neuroblastoma was slowed, but the growth of the A-10 tumor was not affected. An intact functional sympathetic nervous system may be a factor that determines the rate of growth of certain tumors in vivo.

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