Isosorbide Dinitrate in Angina Pectoris

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Abstract
Isosorbide dinitrate, a new member of the nitrate series, seems to be a potent coronary vasodilator. It has a rapid onset of action and a duration which seems comparable to other long acting nitrates recommended for coronary vasodilatation. Although the data obtained in this investigation indicate that the drug produces good to excellent results in 80% of the anginal patients in which it was tested, confirmation based on controlled investigations or by the consensus of clinical impressions will be needed to assess accurately the efficacy of this promising new agent.