The First Catalytic Enantioselective Synthesis of (R)-(+) Lasiodiplodin

Abstract
The first catalytic enantioselective route to (R)-(+) Lasiodiplodin is described. Introduction of the asymmetric center was accomplished by the enantioselective addition of dimethyl zinc to an aldehyde, mediated by a tricarbonyl (η6 arene) chromium(0) catalyst.

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