CALCIUM, PHOSPHORUS AND CHOLESTEROL IN OTOSCLEROSIS

Abstract
In view of the fact that all physiologic and pathologic variations in bone are intimately connected with calcium metabolism, and that otosclerosis is a variation in bony growth, it would seem logical at first thought to search for the blood calcium and phosphorus variations in this disease. This has been done, many observers reporting a diminution in blood calcium (Poos,1Leicher,1aKopetzky and Altman,2etc.), and only one denying this contention (Lindermann3), There are a few uncertain reports on phosphorus. Before I discuss my own observations, it might be well to summarize briefly the latest concepts in the calcium-phosphorus problem. In doing this I borrow freely from Wells,4Aub's Harvey Lecture, 1929,5and Dr. Peters' address before the New York Academy of Medicine, Section on Orthopedics,6all of whom give clear and fairly comprehensive versions of the subject. To simplify this complicated and

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