Biosynthesis of the glycocinnamoylspermidine antibiotic, cinodine.
- 1 January 1984
- journal article
- research article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 37 (9) , 1000-1006
- https://doi.org/10.7164/antibiotics.37.1000
Abstract
The biosynthesis of cinodine [by Nocardia sp.] from a combination of 14C- and 13C-labeled precursors was investigated. Tyrosine was incorporated efficiently into the cinnamoyl moiety and glucosamine was the origin of the 3 carbohydrate moieties. The relationship between the substrate dose and the enrichment of the labeled antibiotic was elucidated so that it is possible to predict both the specific activity and the yield of the antibiotic obtained from the labeled substrates.This publication has 0 references indexed in Scilit: