The von Hippel–Lindau tumor suppressor protein: new insights into oxygen sensing and cancer
- 19 December 2002
- journal article
- review article
- Published by Elsevier in Current Opinion in Genetics & Development
- Vol. 13 (1) , 55-60
- https://doi.org/10.1016/s0959-437x(02)00010-2
Abstract
No abstract availableKeywords
This publication has 54 references indexed in Scilit:
- Oxygen-Dependent Ubiquitination and Degradation of Hypoxia-Inducible Factor Requires Nuclear-Cytoplasmic Trafficking of the von Hippel-Lindau Tumor Suppressor ProteinMolecular and Cellular Biology, 2002
- Protein tyrosine kinase inhibitors: new treatment modalities?Current Opinion in Pharmacology, 2002
- Structural basis for the recognition of hydroxyproline in HIF-1α by pVHLNature, 2002
- Identification of a deubiquitinating enzyme subfamily as substrates of the von Hippel–Lindau tumor suppressorBiochemical and Biophysical Research Communications, 2002
- Independent function of two destruction domains in hypoxia-inducible factor-α chains activated by prolyl hydroxylationThe EMBO Journal, 2001
- Role of transforming growth factor-alpha in von Hippel- Lindau (VHL)-/- clear cell renal carcinoma cell proliferation: A possible mechanism coupling VHL tumor suppressor inactivation and tumorigenesisProceedings of the National Academy of Sciences, 2001
- VHL Induces Renal Cell Differentiation and Growth Arrest through Integration of Cell-Cell and Cell-Extracellular Matrix SignalingMolecular and Cellular Biology, 2001
- Identification of Alternative Spliced Variants of Human Hypoxia-inducible Factor-1αPublished by Elsevier ,2000
- Direct Interaction of the β-Domain of VHL Tumor Suppressor Protein with the Regulatory Domain of Atypical PKC IsotypesBiochemical and Biophysical Research Communications, 1999
- Identification of NEDD8-Conjugation Site in Human Cullin-2Biochemical and Biophysical Research Communications, 1999