Clostridium difficilein Long-Term–Care Facilities for the Elderly
- 1 November 2002
- journal article
- review article
- Published by Cambridge University Press (CUP) in Infection Control & Hospital Epidemiology
- Vol. 23 (11) , 696-703
- https://doi.org/10.1086/501997
Abstract
Antimicrobial agents are among the most frequently prescribed medications in long-term–care facilities (LTCFs). Therefore, it is not surprising thatClostridium difficilecolonization andC. difficile-associated diarrhea (CDAD) occur commonly in elderly LTCF residents.C. difficilehas been identified as the most common cause of non-epidemic acute diarrheal illness in nursing homes, and outbreaks of CDAD in LTCFs have also been recognized. This position paper reviews the epidemiology and clinical features of CDAD in elderly residents of LTCFs and, using available evidence, provides recommendations for the management ofC. difficilein this setting.Keywords
This publication has 111 references indexed in Scilit:
- Comparison of arbitrarily-primed polymerase chain reaction, restriction enzyme analysis and pulsed-field gel electrophoresis for typing Clostridium difficileJournal of Microbiological Methods, 1996
- Comparison of Vancomycin, Teicoplanin, Metronidazole, and Fusidic Acid for the Treatment of Clostridium difficile--Associated DiarrheaClinical Infectious Diseases, 1996
- Use of pulsed-field gel electrophoresis for investigation of an outbreak ofClostridium difficile infection among geriatric patientsEuropean Journal of Clinical Microbiology & Infectious Diseases, 1995
- Diagnosis ofClostridium difficileassociated diarrhea: comparison of three rapid methods employing different markers for detectionCanadian Journal of Microbiology, 1995
- Immunoglobulin G directed against toxins A and B of Clostridium difficile in the general population and patients with antibiotic-associated diarrheaDiagnostic Microbiology and Infectious Disease, 1994
- Control of nosocomial transmission of Clostridium difficile based on sporadic case surveillanceThe American Journal of Medicine, 1991
- Nosocomial Acquisition ofClostridium difficileInfectionNew England Journal of Medicine, 1989
- Epidemiology and prevention ofClostridium difficile infections in a leukemia unitEuropean Journal of Clinical Microbiology & Infectious Diseases, 1987
- CLOSTRIDIUM DIFFICILE DIARRHOEA: A HIGHLY INFECTIOUS ORGANISMAge and Ageing, 1984
- PROSPECTIVE RANDOMISED TRIAL OF METRONIDAZOLE VERSUS VANCOMYCIN FOR CLOSTRIDIUM-DIFFICILE-ASSOCIATED DIARRHOEA AND COLITISThe Lancet, 1983