Crosslinking of collagen gels: photochemical measurements

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Abstract
Clinical investigations have suggested the utility of being able to form, in situ, thin lenticules over the exposed corneal surface from the photopolymerization of a semi-liquid collagen gel. In order to be better able to understand and ultimately control the use of this viscous material for investigations of both the biological stability of these collagen films and their potential in synthetic epikeratoplasty we have studied the photochemical properties of the material. In particular, we have investigated the possibility of using light in the visible wavelength range to initiate gelation of bulk collagen gels, the crosslinking process being effected by added photoinitiators.

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