Synthesis of opiate peptides by a clonal pituitary tumor cell line.
- 1 June 1977
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 74 (6) , 2259-2263
- https://doi.org/10.1073/pnas.74.6.2259
Abstract
Clonal mouse pituitary tumor cells, AtT-20, synthesize at least 4 species of peptides with opiate activity. The endorphin concentration of AtT-20 cells was estimated to be 300-600 pmol/mg of protein. The 2 most abundant endorphins with apparent molecular weights of 1800 and 2400 were purified 300- and 24-fold, respectively; additional minor components were found with apparent molecular weights of > 3000 and < 750.This publication has 20 references indexed in Scilit:
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