THE EFFECTS OF POTASSIUM, COCAINE, URETHANE, AND ALCOHOL ON THE COLD BLOCK IN NERVE

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Abstract
Immersion of the frog sciatic nerve in Ringer''s soln. containing an excess of K (56 mgm. or more %) elevates the temp. at which cold block occurs. The rate and extent of the rise depend on the concn. of K and the time of soaking. Nerves from cold-stored frogs are relatively resistant. Cocaine and urethane act in the same manner as K. No such effect could be demonstrated with ethyl alcohol.